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Lloris awful but Lo Celso tries hard as Mourinho’s men crash out of Europe

first_imgLeipzig player Nordi Mukiele stretchered off after strange injury during Spurs game IT was a terrible night for Spurs as they crashed out of the Champions League to RB Leipzig.Jose Mourinho’s men suffered a 3-0 defeat in Germany, making it a 4-0 loss on aggregate.2 Hugo Lloris made two bad mistakes to give RB Leipzig an early 2-0 lead in GermanyCredit: AFPHere, SunSport’s Anthony Chapman gives his individual player ratings for Spurs.LLORIS: 3Shocking performance from the Spurs captain as his mistakes handed Leipzig an early two-goal lead in Germany.AURIER: 4Hardly threatened despite getting freedom of Spurs’ right wing and was bullied all night by Angelino.TANGANGA: 4Still failing to show why he’s become Mourinho’s golden boy and looked unsure of himself on the big stage.TOTTENHAM NEWS LIVE: FOLLOW LATEST SPURS UPDATESDIER: 4Fans thought he would push up into midfield but all Englishman did was invite pressure towards Spurs’ defence.ALDERWEIRELD: 4In the side to fire long balls to the wing backs but lack of pace saw him closed down almost immediately.SESSEGNON: 4Poor showing despite being allowed to roam even further forward than Aurier and needs a spell with the U23s to get his match fitness up.2 Gio Lo Celso was the only Spurs player who looked to be tryingCredit: PA:Press AssociationWINKS: 4Outclassed in midfield and failed to dictate the pace as he was outshone by Sabitzer.LO CELSO: 6Had a few decent moments and tried his best to drive Spurs on but received hardly any support from team-mates and was shut out on numerous occasions.LAMELA: 4Arguably Spurs’ most intelligent footballer but failed to find any gaps in the Leipzig defence and was too slow to chase down loose balls.LUCAS: 4Spurs’ Champions League hero last season was almost anonymous tonight and barely threatened at all.Most Read In SportTHROUGH ITRobbie Keane reveals Claudine’s father was ’50-50′ in coronavirus battle’I ACCEPT’McGregor accepts Silva fight at UFC catchweight of 176lbs in huge super-fightTOP SELLERGavin Whelan has gone from League of Ireland to David Beckham’s InstagramPicturedA CUT ABOVEMike Tyson shows two-inch cut ‘picked up in training’ ahead of boxing returnPicturedAN EYEFULMeet Playboy model and football agent Anamaria Prodan bidding to buy her own clubI SAW ROORodallega saw Rooney ‘drinking like madman’ & Gerrard ‘on bar dancing shirtless’DELE: 4Devoid of aggression and lacklustre on the ball, his confidence has plummeted since being subbed in the first leg.SUB – FERNANDES: N/AReplaced Lo Celso with ten minutes left as Mourinho decided to give up on the game but had too little time to make an impact.SUB – FAGAN-WALCOTT: N/AOn for Aurier in the 90th minute but would probably have preferred not to have made his debut in the dying moments of a 4-0 Champions League exit.last_img read more

Study explores risk of endometrial cancer among women with postmenopausal bleeding

first_img Source:https://media.jamanetwork.com/news-item/how-common-is-endometrial-cancer-in-women-with-postmenopausal-bleeding/ Aug 7 2018Bottom Line: Postmenopausal bleeding is a common symptom among most women with endometrial cancer but most women with postmenopausal bleeding won’t be diagnosed with endometrial cancer, findings that raise questions about how to best manage postmenopausal bleeding for the early detection of endometrial cancer.Why The Research Is Interesting: Endometrial cancer diagnosed early is often curable with surgery but five-year survival rates plummet for late-stage disease. Accurate estimates of the frequency of postmenopausal bleeding in endometrial cancers and the risk of endometrial cancer in women with postmenopausal bleeding are needed to evaluate whether targeting women with postmenopausal bleeding for early detection is a useful strategy.Related StoriesHow cell-free DNA can be targeted to prevent spread of tumorsSugary drinks linked to cancer finds studyBacteria in the birth canal linked to lower risk of ovarian cancerWho and When: Nearly 41,000 from 129 studies (34,000 women with postmenopausal bleeding and more than 6,000 women with endometrial cancer)What (Measures and Outcomes): Pooled frequency of postmenopausal bleeding in women with endometrial cancer and the risk of endometrial cancer in women with postmenopausal bleedingHow (Study Design): This was a systematic review and meta-analysis. A meta-analysis combines the results of multiple studies identified in a systematic review and quantitatively summarizes the overall association between the same exposure and outcomes measured across all studies.Authors: Megan A. Clarke, Ph.D., M.H.S., of the National Cancer Institute, Rockville, Maryland, and coauthorsResults: The pooled frequency of postmenopausal bleeding among women with endometrial cancer was 91 percent, while the pooled risk of endometrial cancer among women with postmenopausal bleeding was 9 percent.Study Limitations: Some data were inconsistently reported and other available data were insufficient.last_img read more