Modified magazine is for a very niche group of auto enthusiasts. It’s content is centered on high-end vehicle modifications, and Jalopnik suggests that market has a rapidly shrinking ad base, which is forcing Source Interlink to consolidate its Tuner Group.Still, at this time its website and its social properties are live and updated. There is no confirmation on layoffs, however Jalapnik reports that Modified’s editor, Peter Tarach, plus dozens others from various brands have been laid off. It’s also important to note that commenters on the site are confirming Jalopnik’s story and some are disclosing names and titles. FOLIO: will continue to follow this story as it develops. Gawker Media’s Jalopnik reports that Source Interlink has folded its enthusiast automotive title, Modified. It is also rumored that as many as 100 employees from multiple titles have been laid off.FOLIO: has reached out to Source Interlink but the company has not issued a response.Automotive magazines have been amongst the hardest hit in the ad page recession, according to min’s Boxscores. Take for example Crain Communications’, Autoweek, which suffered an 18 percent ad page revenue decline last year. While Source Interlink’s top titles within that category had mixed results. Motor Trend was up in ad pages in 2013 versus 2012 by just under 10 percent. But Hot Rod’s were down by nearly 15 percent in the same period.
Tags “This is one of the most extraordinary black hole systems I’ve ever come across,” explained Associate Professor James Miller-Jones, lead author of a study recently published in Nature.”Like many black holes, it’s feeding on a nearby star, pulling gas away from the star and forming a disk of material that encircles the black hole and spirals towards it under gravity.”What’s different in V404 Cygni is that we think the disk of material and the black hole are misaligned.”This appears to be causing the inner part of the disk to wobble like a spinning top and fire jets out in different directions as it changes orientation.” Think of the black hole in V404 Cygni as a gigantic, light consuming Beyblade that’s starting to run out of juice. It’s no longer spinning straight, it’s wobbling all over the place.You can read more about the ground breaking discovery here, at ICRAR’s official website. Post a comment 14 genius Stephen Hawking quotes that will make you question your place in the universe (pictures) Trippy. ICRAR The year 2019 has been a big one for black holes. To begin with, we saw one for the first time. We also discovered 83 of them at the edge of our universe. No big deal.Now recent research is uncovering more about the insanely dense, spacetime bending bad boys of the universe. Get this: while most black holes are thought to “spin” (thanks to the space dust and gas in orbital motion around the black hole) scientists have discovered a black hole that does things a little differently.V404 Cygni is a binary system in the constellation of Cygnus. At its center is a black hole that is currently in the process of absorbing a low mass nearby star. Astronomers from the International Centre for Radio Astronomy Research in Perth, Western Australia noticed that the black hole in V404 Cygni was spitting out bright jet beams of matter into space. That’s relatively normal, what wasn’t normal was the direction the matter was being sprayed. As a result of the way black holes normally spin, the matter tends to spray out in the same direction. This time it was being sprayed out at different angles. The jets appear to be rapidly rotating.You can see this visualized in the below animation. The conclusion: this black hole is spinning a little differently than the rest. 0 Share your voice 14 Photos Sci-Tech
Study maps hotspots of genetic rearrangement In order to reproduce, the human body must first make either sperm in males or eggs in females and to do that, it must somehow create cells that have just half of that individual’s DNA—the other half will come from the other person during conception. The process by which this occurs is called homologous recombination, where diploid cells undergo cell division resulting in the production of gamete cells. The process is initiated when the body forms breaks in DNA double-strands. It’s in the repair of these breaks that exchanges between chromosomes occur. Recombination occurs at specific sites along chromosomes that are known as hot spots. Finding these hot spots has proved challenging, but now, the researchers with this latest effort report that they have succeeded in creating map of such hot spots which not only allows for looking at how evolution works in new ways, but could prove to be very helpful in better understanding, and possibly treating, some genetic diseases.In their study, the researchers were able to detect the triggers inside the body that led to recombination occurring in human male volunteers—that allowed them to create the maps which show where the recombination events occur. Just looking at the maps, the team notes, allows for a better understanding of the recombination process. One preliminary finding, for example, was that hotspots can be influenced by proteins expressed by a specific gene. de Massy notes that the maps created by the team could very well be used in other mammal species as well, which could help researchers studying how genetic diseases come about better understand where things go wrong, and perhaps, shine a light on possible ways to prevent it from happening. DNA damage resulting in multiple broken chromosomes. Credit: Wikipedia/CC BY-SA 3.0 More information: Recombination initiation maps of individual human genomes, Science 14 November 2014: Vol. 346 no. 6211. DOI: 10.1126/science.1256442ABSTRACTDNA double-strand breaks (DSBs) are introduced in meiosis to initiate recombination and generate crossovers, the reciprocal exchanges of genetic material between parental chromosomes. Here, we present high-resolution maps of meiotic DSBs in individual human genomes. Comparing DSB maps between individuals shows that along with DNA binding by PRDM9, additional factors may dictate the efficiency of DSB formation. We find evidence for both GC-biased gene conversion and mutagenesis around meiotic DSB hotspots, while frequent colocalization of DSB hotspots with chromosome rearrangement breakpoints implicates the aberrant repair of meiotic DSBs in genomic disorders. Furthermore, our data indicate that DSB frequency is a major determinant of crossover rate. These maps provide new insights into the regulation of meiotic recombination and the impact of meiotic recombination on genome function. © 2014 Phys.org Journal information: Science This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Researchers build a map of sites where genetic information is swapped between chromosomes (2014, November 14) retrieved 18 August 2019 from https://phys.org/news/2014-11-sites-genetic-swapped-chromosomes.html (Phys.org)—A small team of researchers in the U.S. has built a detailed map that shows the sites where human genetic information is swapped between chromosomes. In their paper published in the journal Science, the team describe their work and explain how their maps could provide new ways of looking at how such sites influence evolution and possibly genetic diseases. Bernard de Massy, of the Institute of Human Genetics offers an in depth perspective piece on the work done by the team in the same journal edition. Explore further
In a paper published on February 4, Google engineers drafted out plans to forward federated learning at a scale. It showcases the high-level plans, challenges, solutions, and applications. Federated learning was first introduced in 2017 by Google. The idea is to use data from a number of computing devices like smartphones instead of a centralized data source. Federated learning can help with privacy Federated learning can be beneficial as it addresses the privacy concern. Android phones are used for the system where the data is only used but never uploaded to any server. A deep neural network is trained by using TensorFlow on the data stored in the Android phone. The Federated averaging algorithm by Brendan McMahan uses a similar approach as synchronous training. The weights of the neural network are combined in the cloud using Federated Averaging. This creates a global model which is then pushed back to the phones as results/desirable actions. To enhance privacy approaches like differential privacy and Secure aggregation are taken. The paper addresses challenges like time zone differences, connectivity issues, interrupted execution etc,. Their work is mature enough to deploy the system in production for tens of millions of devices. They are working towards supporting billions of devices now. The training protocol The system involves devices and the Federated Learning server communicating availability and the server selecting devices to run a task. A subset of the available devices are selected for a task. The Federated Learning server instructs the devices what computing task to run with a plan. A plan would consist a TensorFlow graph and instructions to execute it. There are three phases for the training to take place: Selection of the devices that meet eligibility criteria Configuring the server with simple or Secure Aggregation Reporting from the devices where reaching a certain number would get the training round started Source: Towards Federated Learning at Scale: System Design The devices are supposed to maintain a repository of the collected data and the applications are responsible to provide data to the Federated Learning runtime as an example store. The Federated Learning server is designed to operate on orders of many magnitudes. Each round can mean updates from devices in the range of KBs to tens of MBs coming going the server. Data collection To avoid harming the phone’s battery life and performance, various analytics are collected in the cloud. The logs don’t contain any personally identifiable information. Secure aggregation Secure aggregation uses encryption to make individual device updates uninspectable. They plant to use it for protection against threats in data centers. Secure aggregation would ensure data encryption even when it is in-memory. Challenges of federated learning Compared to a centralized dataset, federated learning poses a number of challenges. The training data is not inspectable, tooling is required to work with proxy data. Models cannot be run interactively and must be compiled to be deployed in the Federated Learning server. Model resource consumption and runtime compatibility also come into the picture when working with many devices in real-time. Applications of Federated Learning It is best for cases where the data on devices is more relevant than data on servers. Ranking items for better navigation, suggestions for on-device keyboard, and next word prediction. This has already been implemented on Google pixel and Gboard. Future work is to eliminate bias caused be restrictions in device selection, algorithms to support better parallelism (more devices in one round), avoiding retraining already trained tasks on devices, and compression to save bandwidth. Federated computation, not federated learning The authors do no mention machine learning explicitly anywhere in the paper. They believe that the applications of such a model are not limited to machine learning. Federated Computation is the term they want to use for this concept. Federated computation and edge computing Federated learning and edge computing are very similar, there are but subtle differences in the purpose of these two. Federated learning is used to solve problems with specific tasks assigned to endpoint smartphones. Edge computing is for predefined tasks to be processed at end nodes, for example, IoT cameras. Federated learning decentralizes the data used while edge computing decentralizes the task computation to various devices. For more details on the architecture and its working, you can check out the research paper. Read next Technical and hidden debts in machine learning – Google engineers’ give their perspective Researchers introduce a machine learning model where the learning cannot be proved What if AIs could collaborate using human-like values? DeepMind researchers propose a Hanabi platform.
Posted by Share << Previous PostNext Post >> Tags: Air Canada Travelweek Group Wednesday, November 8, 2017 Air Canada, Sky Regional Airlines deal extended to 2027 MONTREAL — Air Canada and Sky Regional Airlines have signed off on a 10-year extension to their capacity purchase agreement.With its fleet comprised exclusively of Embraer 175 jet aircraft that has grown to 25 in recent years, Sky Regional strengthens Air Canada’s competitive position in the rapidly evolving North American regional markets as low cost operators continue to grow, both in Canada and the U.S., said Kevin Howlett, Senior Vice President, Regional Markets and Government Relations at Air Canada.“This 10-year extension to the existing capacity purchase agreement with Sky Regional Airlines underscores our confidence in our Air Canada Express partner to provide a seamless operation and customer experience on behalf of Air Canada in a number of our key domestic and transborder regional markets on a cost competitive basis.”Sky Regional Airlines started flight operations under the Air Canada Express banner on May 1, 2011. The company began with five Bombardier Q400 aircraft flying to and from Toronto’s Billy Bishop Airport and added 15 Embraer 175 aircraft in 2013. The carrier serves the U.S. northeast markets, flying 100+ flights per day into cities such as New York, Boston, Philadelphia, Washington and Chicago. In 2016, Sky Regional added an additional five E175 aircraft to its fleet servicing Jacksonville, Houston, Denver and Atlanta.More news: GLP Worldwide introduces first-ever Wellness programs“We are very pleased that Air Canada has recognized our commitment to the passenger experience, and are looking forward to continued success as Air Canada offers more regional options for Canadians,” said Russell Payson, Chairman, Sky Regional Airlines.In addition to Sky Regional, Air Canada has capacity purchase agreements with its other regional airline partners, Jazz, Air Georgian and EVAS, that operate regional Air Canada Express flights on behalf of Air Canada.